More Than 112 Years of Dedicated Service to Mankind

The Institute has been engaged in several research projects, both internally and externally funded by agencies such as DBT, ICMR, NCDC-IDSP and also private organizations. The recently completed extramural projects carried out in various departments of the Institute are:

Title of Project Funding Agency
NCDC,IDSP-Avian Influenza Surveillance Project MoHFW, GoI, World Bank
Multisite monitoring of Human Influenza viruses, Phase II-ICMR-DHHS,USA ICMR-DHHS- CDC, USA
In vitro and in vivo action of disinfectant sample against Anti HIV activity and Rabies virus. M/s. Bios Agricorp
Post-marketing Clinical Trial for New Rabies Vaccine M/s. Cadila Healthcare
Multisite monitoring of Human Influenza viruses, ICMR- Phase I ICMR-DHHS- CDC

The currently ongoing extramural projects are:

Title of Project Funding Agency
Mechanism based screening and validation of important ayurvedic herbal drugs using radiotracer techniques DST
Evaluation of anti-plasmodial potential of plant derived alkaloids ICMR
NCDC, IDSP-Influenza like illness  Surveillance Project MoHFW, GoI, World Bank
Isolation of tylophorin- the most potent anti-allergic principle for respiratory allergic diseases from Tylophora indica in vitro culture of somatic cells DST

Other internal research projects are focused on specific topics include:

  • HIV
  • Study of Drug-Resistant HIV-1 in the Patient Cohort in Mumbai
  • Assessment of Structural & Functional Alterations of NNRTI resistant HIV-1 Reverse Transcriptase
  • Potential therapeutic activity of gold nanoparticles against HIV
  • Rabies
  • Study of Neuronal Proteome in progress of Rabies
  • Study of immuno-pathogenesis of Rabies Virus infection
  • Assessment of Oxidative-stress in Rabies associated encephalitis in Murine Model.
  • Influenza
  • Molecular characterization of 2009 Pandemic H1N1 Influenza and Seasonal Influenza viruses from patients in and around Mumbai region
  • Assessment of Immunopathogenic markers in Severe Acute Respiratory Illness (SARI) patients.
  • Dengue
  • Molecular characterization of Dengue virus in and around Mumbai
  • Immunogenicity study of recombinant Dengue gene constructs.
  • Anti-Virals
  • Assessment of Potential antiviral activities of phyto-peptides against HIV, Rabies Virus, HSV, Dengue Virus, JEV and Influenza Virus.
  • Immuno-modulators
  • Assessment of Immunomodulatory activity of Natural Compounds.
  • Molecular Diagnostics
  • Molecular characterization of Methicillin Resistant Staphylococcus aureus (MRSA) isolates.
  • Assessment of Loop Mediated Isothermal PCR (LAMP) assay for the diagnosis of Tuberculosis.
  • Vaccine Biology
  • Assessment of BCG as an adjuvant in preparation of Japanese Encephalitis Vaccine.
  • Assessment of Dendritic Cell Vaccines as an immuno-therapeutic agent against Malaria.

Research carried out in each department:

Clinical Pathology
Virology and Immunology
Animal Unit

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