More Than 112 Years of Dedicated Service to Mankind
RESEARCH

The Institute has been engaged in several research projects, both internally and externally funded by agencies such as DBT, ICMR, NCDC-IDSP and also private organizations. The recently completed extramural projects carried out in various departments of the Institute are:

Title of Project Funding Agency
NCDC,IDSP-Avian Influenza Surveillance Project MoHFW, GoI, World Bank
   
Multisite monitoring of Human Influenza viruses, Phase II-ICMR-DHHS,USA ICMR-DHHS- CDC, USA
   
In vitro and in vivo action of disinfectant sample against Anti HIV activity and Rabies virus. M/s. Bios Agricorp
   
Post-marketing Clinical Trial for New Rabies Vaccine M/s. Cadila Healthcare
   
Multisite monitoring of Human Influenza viruses, ICMR- Phase I ICMR-DHHS- CDC

The currently ongoing extramural projects are:

Title of Project Funding Agency
Mechanism based screening and validation of important ayurvedic herbal drugs using radiotracer techniques DST
   
Evaluation of anti-plasmodial potential of plant derived alkaloids ICMR
   
NCDC, IDSP-Influenza like illness  Surveillance Project MoHFW, GoI, World Bank
   
Isolation of tylophorin- the most potent anti-allergic principle for respiratory allergic diseases from Tylophora indica in vitro culture of somatic cells DST

Other internal research projects are focused on specific topics include:

  • HIV
  • Study of Drug-Resistant HIV-1 in the Patient Cohort in Mumbai
  • Assessment of Structural & Functional Alterations of NNRTI resistant HIV-1 Reverse Transcriptase
  • Potential therapeutic activity of gold nanoparticles against HIV
  • Rabies
  • Study of Neuronal Proteome in progress of Rabies
  • Study of immuno-pathogenesis of Rabies Virus infection
  • Assessment of Oxidative-stress in Rabies associated encephalitis in Murine Model.
  • Influenza
  • Molecular characterization of 2009 Pandemic H1N1 Influenza and Seasonal Influenza viruses from patients in and around Mumbai region
  • Assessment of Immunopathogenic markers in Severe Acute Respiratory Illness (SARI) patients.
  • Dengue
  • Molecular characterization of Dengue virus in and around Mumbai
  • Immunogenicity study of recombinant Dengue gene constructs.
  • Anti-Virals
  • Assessment of Potential antiviral activities of phyto-peptides against HIV, Rabies Virus, HSV, Dengue Virus, JEV and Influenza Virus.
  • Immuno-modulators
  • Assessment of Immunomodulatory activity of Natural Compounds.
  • Molecular Diagnostics
  • Molecular characterization of Methicillin Resistant Staphylococcus aureus (MRSA) isolates.
  • Assessment of Loop Mediated Isothermal PCR (LAMP) assay for the diagnosis of Tuberculosis.
  • Vaccine Biology
  • Assessment of BCG as an adjuvant in preparation of Japanese Encephalitis Vaccine.
  • Assessment of Dendritic Cell Vaccines as an immuno-therapeutic agent against Malaria.

Research carried out in each department:

Biochemistry
Chemotherapy
Clinical Pathology
Virology and Immunology
Animal Unit
Zoonosis

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