The Institute has been engaged in several research projects, both internally and externally funded by agencies such as DBT, ICMR, NCDC-IDSP and also private organizations. The recently completed extramural projects carried out in various departments of the Institute are:
| Title of Project |
Funding Agency |
| NCDC,IDSP-Avian Influenza Surveillance Project |
MoHFW, GoI, World Bank |
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| Multisite monitoring of Human Influenza viruses, Phase II-ICMR-DHHS,USA |
ICMR-DHHS- CDC, USA |
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| In vitro and in vivo action of disinfectant sample against Anti HIV activity and Rabies virus. |
M/s. Bios Agricorp |
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| Post-marketing Clinical Trial for New Rabies Vaccine |
M/s. Cadila Healthcare |
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| Multisite monitoring of Human Influenza viruses, ICMR- Phase I |
ICMR-DHHS- CDC |
The currently ongoing extramural projects are:
| Title of Project |
Funding Agency |
| Mechanism based screening and validation of important ayurvedic herbal drugs using radiotracer techniques |
DST |
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| Evaluation of anti-plasmodial potential of plant derived alkaloids |
ICMR |
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| NCDC, IDSP-Influenza like illness Surveillance Project |
MoHFW, GoI, World Bank |
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| Isolation of tylophorin- the most potent anti-allergic principle for respiratory allergic diseases from Tylophora indica in vitro culture of somatic cells |
DST |
Other internal research projects are focused on specific topics include:
- HIV
- Study of Drug-Resistant HIV-1 in the Patient Cohort in Mumbai
- Assessment of Structural & Functional Alterations of NNRTI resistant HIV-1 Reverse Transcriptase
- Potential therapeutic activity of gold nanoparticles against HIV
- Rabies
- Study of Neuronal Proteome in progress of Rabies
- Study of immuno-pathogenesis of Rabies Virus infection
- Assessment of Oxidative-stress in Rabies associated encephalitis in Murine Model.
- Influenza
- Molecular characterization of 2009 Pandemic H1N1 Influenza and Seasonal Influenza viruses from patients in and around Mumbai region
- Assessment of Immunopathogenic markers in Severe Acute Respiratory Illness (SARI) patients.
- Dengue
- Molecular characterization of Dengue virus in and around Mumbai
- Immunogenicity study of recombinant Dengue gene constructs.
- Anti-Virals
- Assessment of Potential antiviral activities of phyto-peptides against HIV, Rabies Virus, HSV, Dengue Virus, JEV and Influenza Virus.
- Immuno-modulators
- Assessment of Immunomodulatory activity of Natural Compounds.
- Molecular Diagnostics
- Molecular characterization of Methicillin Resistant Staphylococcus aureus (MRSA) isolates.
- Assessment of Loop Mediated Isothermal PCR (LAMP) assay for the diagnosis of Tuberculosis.
- Vaccine Biology
- Assessment of BCG as an adjuvant in preparation of Japanese Encephalitis Vaccine.
- Assessment of Dendritic Cell Vaccines as an immuno-therapeutic agent against Malaria.
Research carried out in each department:
Biochemistry
Chemotherapy
Clinical Pathology
Virology and Immunology
Animal Unit
Zoonosis |
